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IL-21/IL-21R inhibit tumor growth and invasion in non-small cell lung cancer cells via suppressing Wnt/β-catenin signaling and PD-L1 expression

Lung cancer is considered to be one of the world's deadliest diseases, with non-small cell lung cancer (NSCLC) accounting for 85% of all lung cancer cases. The present study aimed to investigate the role and underlying mechanisms of interleukin-21 (IL-21), and its receptor IL-21R, in NSCLC. Lun...

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Detalles Bibliográficos
Autores principales: Xue, Dan, Yang, Ping, Wei, Qiongying, Li, Xiaoping, Lin, Lan, Lin, Tingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777672/
https://www.ncbi.nlm.nih.gov/pubmed/31573051
http://dx.doi.org/10.3892/ijmm.2019.4354