Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies

The synucleinopathies Parkinson’s disease (PD) and Multiple system atrophy (MSA) — characterized by α-synuclein intracytoplasmic inclusions into, respectively, neurons and oligodendrocytes — are associated with impairment of the autophagy-lysosomal pathways (ALP). Increased expression of the master...

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Detalles Bibliográficos
Autores principales: Arotcarena, Marie-Laure, Bourdenx, Mathieu, Dutheil, Nathalie, Thiolat, Marie-Laure, Doudnikoff, Evelyne, Dovero, Sandra, Ballabio, Andrea, Fernagut, Pierre-Olivier, Meissner, Wassilios G., Bezard, Erwan, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777809/
https://www.ncbi.nlm.nih.gov/pubmed/31434803
http://dx.doi.org/10.1172/jci.insight.129719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777809/
https://www.ncbi.nlm.nih.gov/pubmed/31434803
http://dx.doi.org/10.1172/jci.insight.129719

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