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Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease

Drug-induced interstitial lung disease (DIILD) is a serious side effect of chemotherapy in cancer patients with an extremely high mortality rate. In this study, to identify genetic variants with greater risk of DIILD, we carried out whole genome sequencing (WGS) of germline DNA samples from 26 patie...

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Detalles Bibliográficos
Autores principales: Udagawa, Chihiro, Horinouchi, Hidehito, Shiraishi, Kouya, Kohno, Takashi, Okusaka, Takuji, Ueno, Hideki, Tamura, Kenji, Ohe, Yuichiro, Zembutsu, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777826/
https://www.ncbi.nlm.nih.gov/pubmed/31584970
http://dx.doi.org/10.1371/journal.pone.0223371