NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

Iron is essential for survival of most organisms. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1. We previously showed that hif-1 mutants are developmentally delayed when grown under iron limitati...

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Detalles Bibliográficos
Autores principales: Rajan, Malini, Anderson, Cole P, Rindler, Paul M, Romney, Steven Joshua, Ferreira dos Santos, Maria C, Gertz, Jason, Leibold, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777940/
https://www.ncbi.nlm.nih.gov/pubmed/31532389
http://dx.doi.org/10.7554/eLife.44674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777940/
https://www.ncbi.nlm.nih.gov/pubmed/31532389
http://dx.doi.org/10.7554/eLife.44674

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