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NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling
Iron is essential for survival of most organisms. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1. We previously showed that hif-1 mutants are developmentally delayed when grown under iron limitati...
Autores principales: | Rajan, Malini, Anderson, Cole P, Rindler, Paul M, Romney, Steven Joshua, Ferreira dos Santos, Maria C, Gertz, Jason, Leibold, Elizabeth A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777940/ https://www.ncbi.nlm.nih.gov/pubmed/31532389 http://dx.doi.org/10.7554/eLife.44674 |
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