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Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance

Myogenic vasoconstriction is an autoregulatory function of small arteries. Recently, G-protein-coupled receptors have been involved in myogenic vasoconstriction, but the downstream signalling mechanisms and the in-vivo-function of this myogenic autoregulation are poorly understood. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Chennupati, Ramesh, Wirth, Angela, Favre, Julie, Li, Rui, Bonnavion, Rémy, Jin, Young-June, Wietelmann, Astrid, Schweda, Frank, Wettschureck, Nina, Henrion, Daniel, Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777979/
https://www.ncbi.nlm.nih.gov/pubmed/31549965
http://dx.doi.org/10.7554/eLife.49374