A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing

Delivery technologies for the CRISPR-Cas9 gene editing system often require viral vectors, which pose safety concerns for therapeutic genome editing(1). Alternatively, cationic liposomal components or polymers can be used to encapsulate multiple CRISPR components into large particles (typically >...

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Detalles Bibliográficos
Autores principales: Chen, Guojun, Abdeen, Amr A., Wang, Yuyuan, Shahi, Pawan K., Robertson, Samantha, Xie, Ruosen, Suzuki, Masatoshi, Pattnaik, Bikash R., Saha, Krishanu, Gong, Shaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778035/
https://www.ncbi.nlm.nih.gov/pubmed/31501532
http://dx.doi.org/10.1038/s41565-019-0539-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778035/
https://www.ncbi.nlm.nih.gov/pubmed/31501532
http://dx.doi.org/10.1038/s41565-019-0539-2

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