Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing

The selective regulation of bacteria in complex microbial populations is key to controlling pathogenic bacteria. CRISPR nucleases can be programmed to kill bacteria, but require an efficient and broad-host range delivery system to be effective. Here, using an Escherichia coli and Salmonella enterica...

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Detalles Bibliográficos
Autores principales: Hamilton, Thomas A., Pellegrino, Gregory M., Therrien, Jasmine A., Ham, Dalton T., Bartlett, Peter C., Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778077/
https://www.ncbi.nlm.nih.gov/pubmed/31586051
http://dx.doi.org/10.1038/s41467-019-12448-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778077/
https://www.ncbi.nlm.nih.gov/pubmed/31586051
http://dx.doi.org/10.1038/s41467-019-12448-3

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