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Monitoring cytosolic H(2)O(2) fluctuations arising from altered plasma membrane gradients or from mitochondrial activity

Genetically encoded probes monitoring H(2)O(2) fluctuations in living organisms are key to decipher redox signaling events. Here we use a new probe, roGFP2-Tpx1.C169S, to monitor pre-toxic fluctuations of peroxides in fission yeast, where the concentrations linked to signaling or to toxicity have be...

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Detalles Bibliográficos
Autores principales: Carmona, Mercè, de Cubas, Laura, Bautista, Eric, Moral-Blanch, Marta, Medraño-Fernández, Iria, Sitia, Roberto, Boronat, Susanna, Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778086/
https://www.ncbi.nlm.nih.gov/pubmed/31586057
http://dx.doi.org/10.1038/s41467-019-12475-0