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Monitoring cytosolic H(2)O(2) fluctuations arising from altered plasma membrane gradients or from mitochondrial activity
Genetically encoded probes monitoring H(2)O(2) fluctuations in living organisms are key to decipher redox signaling events. Here we use a new probe, roGFP2-Tpx1.C169S, to monitor pre-toxic fluctuations of peroxides in fission yeast, where the concentrations linked to signaling or to toxicity have be...
Autores principales: | Carmona, Mercè, de Cubas, Laura, Bautista, Eric, Moral-Blanch, Marta, Medraño-Fernández, Iria, Sitia, Roberto, Boronat, Susanna, Ayté, José, Hidalgo, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778086/ https://www.ncbi.nlm.nih.gov/pubmed/31586057 http://dx.doi.org/10.1038/s41467-019-12475-0 |
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