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Mechanical strain promotes skin fibrosis through LRG-1 induction mediated by ELK1 and ERK signalling

Biomechanical force and pathological angiogenesis are dominant features in fibro-proliferative disorders. Understanding the role and regulation of the mechanical microenvironment in which pathological angiogenesis occurs is an important challenge when investigating numerous angiogenesis-related dise...

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Detalles Bibliográficos
Autores principales: Gao, Ya, Zhou, Jia, Xie, Zhibo, Wang, Jing, Ho, Chia-kang, Zhang, Yifan, Li, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778114/
https://www.ncbi.nlm.nih.gov/pubmed/31602408
http://dx.doi.org/10.1038/s42003-019-0600-6