Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

Fibroblast to myofibroblast differentiation is crucial for the initial healing response but excessive myofibroblast activation leads to pathological fibrosis. Therefore, it is imperative to understand the mechanisms underlying myofibroblast formation. Here we report that mitochondrial calcium ((m)Ca...

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Detalles Bibliográficos
Autores principales: Lombardi, Alyssa A., Gibb, Andrew A., Arif, Ehtesham, Kolmetzky, Devin W., Tomar, Dhanendra, Luongo, Timothy S., Jadiya, Pooja, Murray, Emma K., Lorkiewicz, Pawel K., Hajnóczky, György, Murphy, Elizabeth, Arany, Zoltan P., Kelly, Daniel P., Margulies, Kenneth B., Hill, Bradford G., Elrod, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778142/
https://www.ncbi.nlm.nih.gov/pubmed/31586055
http://dx.doi.org/10.1038/s41467-019-12103-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778142/
https://www.ncbi.nlm.nih.gov/pubmed/31586055
http://dx.doi.org/10.1038/s41467-019-12103-x

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