Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway

The dynamics of aggregation and structural diversification of misfolded, host-encoded proteins in neurodegenerative diseases are poorly understood. In many of these disorders, including Alzheimer’s, Parkinson’s and prion diseases, the misfolded proteins are self-organized into conformationally disti...

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Detalles Bibliográficos
Autores principales: Igel-Egalon, Angélique, Laferrière, Florent, Moudjou, Mohammed, Bohl, Jan, Mezache, Mathieu, Knäpple, Tina, Herzog, Laetitia, Reine, Fabienne, Jas-Duval, Christelle, Doumic, Marie, Rezaei, Human, Béringue, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778151/
https://www.ncbi.nlm.nih.gov/pubmed/31602412
http://dx.doi.org/10.1038/s42003-019-0608-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778151/
https://www.ncbi.nlm.nih.gov/pubmed/31602412
http://dx.doi.org/10.1038/s42003-019-0608-y

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