Oral and intravenous transmission of α-synuclein fibrils to mice

Parkinson’s disease and related disorders are neuropathologically characterized by cellular deposits of misfolded and aggregated α-synuclein in the CNS. Disease-associated α-synuclein adopts a conformation that causes it to form oligomers and fibrils, which have reduced solubility, become hyperphosp...

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Detalles Bibliográficos
Autores principales: Lohmann, Stephanie, Bernis, Maria E., Tachu, Babila J., Ziemski, Alexandra, Grigoletto, Jessica, Tamgüney, Gültekin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778172/
https://www.ncbi.nlm.nih.gov/pubmed/31230104
http://dx.doi.org/10.1007/s00401-019-02037-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778172/
https://www.ncbi.nlm.nih.gov/pubmed/31230104
http://dx.doi.org/10.1007/s00401-019-02037-5

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