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Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are clinically and neuropathologically highly related α-synucleinopathies that collectively constitute the second leading cause of neurodegenerative dementias. Genetic and neuropathological studies directly implicate α-synuclein...

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Detalles Bibliográficos
Autores principales: Singh, Balvindar, Covelo, Ana, Martell-Martínez, Héctor, Nanclares, Carmen, Sherman, Mathew A., Okematti, Emmanuel, Meints, Joyce, Teravskis, Peter J., Gallardo, Christopher, Savonenko, Alena V., Benneyworth, Michael A., Lesné, Sylvain E., Liao, Dezhi, Araque, Alfonso, Lee, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778173/
https://www.ncbi.nlm.nih.gov/pubmed/31168644
http://dx.doi.org/10.1007/s00401-019-02032-w