Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections

Staphylococcus aureus small-colony variants (SCVs) are associated with unusually chronic and persistent infections despite active antibiotic treatment. The molecular basis for this clinically important phenomenon is poorly understood, hampered by the instability of the SCV phenotype. Here we investi...

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Detalles Bibliográficos
Autores principales: Guérillot, Romain, Kostoulias, Xenia, Donovan, Liam, Li, Lucy, Carter, Glen P., Hachani, Abderrahman, Vandelannoote, Koen, Giulieri, Stefano, Monk, Ian R., Kunimoto, Mayu, Starrs, Lora, Burgio, Gaétan, Seemann, Torsten, Peleg, Anton Y., Stinear, Timothy P., Howden, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778178/
https://www.ncbi.nlm.nih.gov/pubmed/31527262
http://dx.doi.org/10.1073/pnas.1904861116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778178/
https://www.ncbi.nlm.nih.gov/pubmed/31527262
http://dx.doi.org/10.1073/pnas.1904861116

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