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Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections
Staphylococcus aureus small-colony variants (SCVs) are associated with unusually chronic and persistent infections despite active antibiotic treatment. The molecular basis for this clinically important phenomenon is poorly understood, hampered by the instability of the SCV phenotype. Here we investi...
Autores principales: | Guérillot, Romain, Kostoulias, Xenia, Donovan, Liam, Li, Lucy, Carter, Glen P., Hachani, Abderrahman, Vandelannoote, Koen, Giulieri, Stefano, Monk, Ian R., Kunimoto, Mayu, Starrs, Lora, Burgio, Gaétan, Seemann, Torsten, Peleg, Anton Y., Stinear, Timothy P., Howden, Benjamin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778178/ https://www.ncbi.nlm.nih.gov/pubmed/31527262 http://dx.doi.org/10.1073/pnas.1904861116 |
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