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Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice

Dietary restriction induces beneficial metabolic changes and prevents age-related deterioration. Mesencephalic astrocyte-derived neurotrophic factor (MANF) shows protective effects on cells in various models of degenerative diseases. Here we studied whether circulating concentrations of MANF are ass...

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Detalles Bibliográficos
Autores principales: Galli, Emilia, Rossi, Jari, Neumann, Thomas, Andressoo, Jaan-Olle, Drinda, Stefan, Lindholm, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778185/
https://www.ncbi.nlm.nih.gov/pubmed/31586115
http://dx.doi.org/10.1038/s41598-019-50841-6