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3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumors
Dynamic alterations in the unique brain extracellular matrix (ECM) are involved in malignant brain tumors. Yet studies of brain ECM roles in tumor cell behavior have been difficult due to lack of access to the human brain. We present a tunable 3D bioengineered brain tissue platform by integrating mi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778192/ https://www.ncbi.nlm.nih.gov/pubmed/31586101 http://dx.doi.org/10.1038/s41467-019-12420-1 |