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Restoration of visual function by transplantation of optogenetically engineered photoreceptors

A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photoreceptors, is the difficulty in inducing the grafted cells to grow and maintain light sensitive outer segments in the host retina, which depends on proper interaction with the underlying...

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Detalles Bibliográficos
Autores principales: Garita-Hernandez, Marcela, Lampič, Maruša, Chaffiol, Antoine, Guibbal, Laure, Routet, Fiona, Santos-Ferreira, Tiago, Gasparini, Sylvia, Borsch, Oliver, Gagliardi, Giuliana, Reichman, Sacha, Picaud, Serge, Sahel, José-Alain, Goureau, Olivier, Ader, Marius, Dalkara, Deniz, Duebel, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778196/
https://www.ncbi.nlm.nih.gov/pubmed/31586094
http://dx.doi.org/10.1038/s41467-019-12330-2