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The protective role of microRNA-21 against coxsackievirus B3 infection through targeting the MAP2K3/P38 MAPK signaling pathway

BACKGROUND: The P38 mitogen-activated protein kinase (MAPK) pathway plays an essential role in CVB3-induced diseases. We previously demonstrated microRNA-21 has potential inhibitory effect on the MAP2K3 which locates upstream of P38 MAPK and was upregulated in mouse hearts upon CVB3 infection. Howev...

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Detalles Bibliográficos
Autores principales: He, Feng, Xiao, Zonghui, Yao, Hailan, Li, Sen, Feng, Miao, Wang, Wei, Liu, Zhewei, Liu, Zhuo, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778380/
https://www.ncbi.nlm.nih.gov/pubmed/31585536
http://dx.doi.org/10.1186/s12967-019-2077-y