Basic Fibroblast Growth Factor Reduces Permeability and Apoptosis of Human Brain Microvascular Endothelial Cells in Response to Oxygen and Glucose Deprivation Followed by Reoxygenation via the Fibroblast Growth Factor Receptor 1 (FGFR1)/ERK Pathway

BACKGROUND: Disruption of the blood–brain barrier (BBB) is a mechanism in the pathogenesis of traumatic brain injury. Basic fibroblast growth factor (bFGF) is expressed in angiogenesis, neurogenesis, and neuronal survival. This study aimed to investigate the role of bFGF in vitro in human brain micr...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Zhang, Hongguang, Zhang, Qingtao, Zhou, Wei, Deng, Yongbing, Hu, Xi, Zhang, Lianyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778414/
https://www.ncbi.nlm.nih.gov/pubmed/31551405
http://dx.doi.org/10.12659/MSM.918626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778414/
https://www.ncbi.nlm.nih.gov/pubmed/31551405
http://dx.doi.org/10.12659/MSM.918626

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