G-tract RNA removes Polycomb Repressive Complex 2 from genes

Polycomb Repressive Complex 2 (PRC2) maintains repression of cell type-specific genes but also associates with genes ectopically in cancer. While it is currently unknown how PRC2 is removed from genes, such knowledge would be useful for the targeted reversal of deleterious PRC2 recruitment events. H...

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Detalles Bibliográficos
Autores principales: Beltran, Manuel, Tavares, Manuel, Justin, Neil, Khandelwal, Garima, Ambrose, John, Foster, Benjamin M., Worlock, Kaylee B., Tvardovskiy, Andrey, Kunzelmann, Simone, Herrero, Javier, Bartke, Till, Gamblin, Steven J., Wilson, Jon R., Jenner, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778522/
https://www.ncbi.nlm.nih.gov/pubmed/31548724
http://dx.doi.org/10.1038/s41594-019-0293-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778522/
https://www.ncbi.nlm.nih.gov/pubmed/31548724
http://dx.doi.org/10.1038/s41594-019-0293-z

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