An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

INTRODUCTION: Noise-induced hearing loss (NIHL) is an increasing problem in society and accounts for a third of all cases of acquired hearing loss. NIHL is caused by formation of reactive oxygen species (ROS) in the cochlea causing oxidative stress. Hydrogen gas (H(2)) can alleviate the damage cause...

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Detalles Bibliográficos
Autores principales: Pirttilä, Kristian, Videhult Pierre, Pernilla, Haglöf, Jakob, Engskog, Mikael, Hedeland, Mikael, Laurell, Göran, Arvidsson, Torbjörn, Pettersson, Curt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778533/
https://www.ncbi.nlm.nih.gov/pubmed/31587113
http://dx.doi.org/10.1007/s11306-019-1595-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778533/
https://www.ncbi.nlm.nih.gov/pubmed/31587113
http://dx.doi.org/10.1007/s11306-019-1595-1

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