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Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks

Serum response factor (SRF) is a major transcription factor that regulates the expression of several plasticity-associated genes in the brain. Although the developmental expression of SRF in excitatory neurons is crucial for establishing proper hippocampal circuitry, no substantial evidence of its r...

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Detalles Bibliográficos
Autores principales: Nader, Karolina, Krysiak, Anna, Beroun, Anna, Pekala, Martyna, Szymanska, Magda, Kuzniewska, Bozena, Radwanska, Kasia, Kaczmarek, Leszek, Kalita, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778544/
https://www.ncbi.nlm.nih.gov/pubmed/31375980
http://dx.doi.org/10.1007/s00429-019-01925-6