H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice

Epigenetic dysregulation of long noncoding RNA H19 was recently found to be associated with calcific aortic valve disease (CAVD) in humans by repressing NOTCH1 transcription. This finding offers a possible epigenetic explanation for the abundance of cases of CAVD that are not explained by any clear...

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Detalles Bibliográficos
Autores principales: Vander Roest, Mark, Krapp, Christopher, Thorvaldsen, Joanne L., Bartolomei, Marisa S., Merryman, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597/
https://www.ncbi.nlm.nih.gov/pubmed/31609547
http://dx.doi.org/10.14814/phy2.14244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597/
https://www.ncbi.nlm.nih.gov/pubmed/31609547
http://dx.doi.org/10.14814/phy2.14244

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