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H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice
Epigenetic dysregulation of long noncoding RNA H19 was recently found to be associated with calcific aortic valve disease (CAVD) in humans by repressing NOTCH1 transcription. This finding offers a possible epigenetic explanation for the abundance of cases of CAVD that are not explained by any clear...
Autores principales: | Vander Roest, Mark, Krapp, Christopher, Thorvaldsen, Joanne L., Bartolomei, Marisa S., Merryman, W. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597/ https://www.ncbi.nlm.nih.gov/pubmed/31609547 http://dx.doi.org/10.14814/phy2.14244 |
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