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Impact of arrhythmogenic calmodulin variants on small conductance Ca(2+)‐activated K(+) (SK3) channels

Calmodulin (CaM) is a ubiquitous Ca(2+)‐sensing protein regulating many important cellular processes. Several CaM‐associated variants have been identified in a small group of patients with cardiac arrhythmias. The mechanism remains largely unknown, even though a number of ion channels, including the...

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Detalles Bibliográficos
Autores principales: Saljic, Arnela, Muthukumarasamy, Kalai Mangai, la Cour, Jonas Marstrand, Boddum, Kim, Grunnet, Morten, Berchtold, Martin Werner, Jespersen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778599/
https://www.ncbi.nlm.nih.gov/pubmed/31587513
http://dx.doi.org/10.14814/phy2.14210