Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Wenyu, Sakai, Katsuya, Sato, Hiroki, Imamura, Ryu, Jangphattananont, Nawaphat, Takagi, Junichi, Nishita, Michiru, Minami, Yasuhiro, Matsumoto, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778621/
https://www.ncbi.nlm.nih.gov/pubmed/31342590
http://dx.doi.org/10.1111/cas.14142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778621/
https://www.ncbi.nlm.nih.gov/pubmed/31342590
http://dx.doi.org/10.1111/cas.14142

Ejemplares similares