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Barcode sequencing identifies resistant mechanisms to epidermal growth factor receptor inhibitors in circulating tumor DNA of lung cancer patients

Most patients with epidermal growth factor receptor (EGFR) mutation‐positive non‐small cell lung cancer (NSCLC) will inevitably develop acquired resistance induced by treatment with EGFR tyrosine kinase inhibitors (EGFR‐TKI). The mechanisms of resistance to EGFR‐TKI are multifactorial, and the detec...

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Detalles Bibliográficos
Autores principales: Kitazono, Satoru, Sakai, Kazuko, Yanagitani, Noriko, Ariyasu, Ryo, Yoshizawa, Takahiro, Dotsu, Yosuke, Koyama, Junji, Saiki, Masafumi, Sonoda, Tomoaki, Nishikawa, Shingo, Uchibori, Ken, Horiike, Atsushi, Nishio, Kazuto, Nishio, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778626/
https://www.ncbi.nlm.nih.gov/pubmed/31361375
http://dx.doi.org/10.1111/cas.14153