Evaluation of the antitumor mechanism of antibody‐drug conjugates against tissue factor in stroma‐rich allograft models

Tissue factor (TF) is known to be overexpressed in various cancers including pancreatic cancer. The upregulation of TF expression has been observed not only in tumor cells, but also in tumor stromal cells. Because of the potential of TF as a delivery target, several studies investigated the effectiv...

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Detalles Bibliográficos
Autores principales: Tsumura, Ryo, Manabe, Shino, Takashima, Hiroki, Koga, Yoshikatsu, Yasunaga, Masahiro, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778651/
https://www.ncbi.nlm.nih.gov/pubmed/31348600
http://dx.doi.org/10.1111/cas.14146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778651/
https://www.ncbi.nlm.nih.gov/pubmed/31348600
http://dx.doi.org/10.1111/cas.14146

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