HIF inhibitor topotecan has a neuroprotective effect in a murine retinal ischemia-reperfusion model

PURPOSE: The therapeutic approach for retinal ganglion cell (RGC) degeneration has not been fully established. Recently, it has been reported that hypoxia-inducible factor (HIF) may be involved with retinal neurodegeneration. In this study, we investigated neuroprotective effects of a HIF inhibitor...

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Detalles Bibliográficos
Autores principales: Kunimi, Hiromitsu, Miwa, Yukihiro, Katada, Yusaku, Tsubota, Kazuo, Kurihara, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779112/
https://www.ncbi.nlm.nih.gov/pubmed/31592359
http://dx.doi.org/10.7717/peerj.7849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779112/
https://www.ncbi.nlm.nih.gov/pubmed/31592359
http://dx.doi.org/10.7717/peerj.7849

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