A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis

There is an urgent need for new anti-tubercular agents which can lead to a shortened treatment time by targeting persistent or non-replicating bacilli. In order to assess compound activity against non-replicating Mycobacterium tuberculosis, we developed a method to detect the bactericidal activity o...

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Detalles Bibliográficos
Autores principales: Early, Julie V., Mullen, Steven, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779252/
https://www.ncbi.nlm.nih.gov/pubmed/31589621
http://dx.doi.org/10.1371/journal.pone.0222970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779252/
https://www.ncbi.nlm.nih.gov/pubmed/31589621
http://dx.doi.org/10.1371/journal.pone.0222970

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