Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform

Ligand binding to death receptors activates apoptosis in cancer cells. Stimulation of death receptors results in the formation of intracellular multiprotein platforms that either activate the apoptotic initiator Caspase-8 to trigger cell death, or signal through kinases to initiate inflammatory and...

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Detalles Bibliográficos
Autores principales: Matveeva, Anna, Fichtner, Michael, McAllister, Katherine, McCann, Christopher, Sturrock, Marc, Longley, Daniel B., Prehn, Jochen H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779275/
https://www.ncbi.nlm.nih.gov/pubmed/31553717
http://dx.doi.org/10.1371/journal.pcbi.1007374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779275/
https://www.ncbi.nlm.nih.gov/pubmed/31553717
http://dx.doi.org/10.1371/journal.pcbi.1007374

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