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Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing

The analysis of circulating cell-free DNA (cfDNA) extracted from peripheral blood can serve as a minimally invasive alternative to tumor tissue biopsies in cases with impaired access to tissue. Its clinical utility has been well demonstrated for EGFR T790M testing in lung cancer patients suffering p...

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Detalles Bibliográficos
Autores principales: Streubel, Anna, Stenzinger, Albrecht, Stephan-Falkenau, Susann, Kollmeier, Jens, Misch, Daniel, Blum, Torsten Gerriet, Bauer, Torsten, Landt, Olfert, Am Ende, Alexander, Schirmacher, Peter, Mairinger, Thomas, Endris, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779285/
https://www.ncbi.nlm.nih.gov/pubmed/31620244
http://dx.doi.org/10.18632/oncotarget.27183