Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

PURPOSE: Age-related macular degeneration (AMD) is the worldwide leading cause of blindness among the elderly. Although genome-wide association studies (GWAS) have identified AMD risk variants, their roles in disease etiology are not well-characterized, and they only explain a portion of AMD heritab...

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Detalles Bibliográficos
Autores principales: Waksmunski, Andrea R., Grunin, Michelle, Kinzy, Tyler G., Igo, Robert P., Haines, Jonathan L., Cooke Bailey, Jessica N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779289/
https://www.ncbi.nlm.nih.gov/pubmed/31560769
http://dx.doi.org/10.1167/iovs.19-27827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779289/
https://www.ncbi.nlm.nih.gov/pubmed/31560769
http://dx.doi.org/10.1167/iovs.19-27827

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