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Cell fishing: A similarity based approach and machine learning strategy for multiple cell lines-compound sensitivity prediction
The prediction of cell-lines sensitivity to a given set of compounds is a very important factor in the optimization of in-vitro assays. To date, the most common prediction strategies are based upon machine learning or other quantitative structure-activity relationships (QSAR) based approaches. In th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779297/ https://www.ncbi.nlm.nih.gov/pubmed/31589649 http://dx.doi.org/10.1371/journal.pone.0223276 |