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Effect of methylation of adenine N(6) on kink turn structure depends on location

N(6)-methyladenine is the most common covalent modification in cellular RNA species, with demonstrated functional consequences. At the molecular level this methylation could alter local RNA structure, and/or modulate the binding of specific proteins. We have previously shown that trans-Hoogsteen-sug...

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Detalles Bibliográficos
Autores principales: Ashraf, Saira, Huang, Lin, Lilley, David M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779385/
https://www.ncbi.nlm.nih.gov/pubmed/31234702
http://dx.doi.org/10.1080/15476286.2019.1630797