Targeted sequencing reveals expanded genetic diversity of human transfer RNAs

Transfer RNAs are required to translate genetic information into proteins as well as regulate other cellular processes. Nucleotide changes in tRNAs can result in loss or gain of function that impact the composition and fidelity of the proteome. Despite links between tRNA variation and disease, the i...

Descripción completa

Detalles Bibliográficos
Autores principales: Berg, Matthew D., Giguere, Daniel J., Dron, Jacqueline S., Lant, Jeremy T., Genereaux, Julie, Liao, Calwing, Wang, Jian, Robinson, John F., Gloor, Gregory B., Hegele, Robert A., O’Donoghue, Patrick, Brandl, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779403/
https://www.ncbi.nlm.nih.gov/pubmed/31407949
http://dx.doi.org/10.1080/15476286.2019.1646079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779403/
https://www.ncbi.nlm.nih.gov/pubmed/31407949
http://dx.doi.org/10.1080/15476286.2019.1646079

Ejemplares similares