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Stimulation of Piezo1 by mechanical signals promotes bone anabolism

Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood. Osteocytes reside in bone matrix, sense changes in mechanical load, and produce signals that alter bone formation by osteoblasts. We report...

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Detalles Bibliográficos
Autores principales: Li, Xuehua, Han, Li, Nookaew, Intawat, Mannen, Erin, Silva, Matthew J, Almeida, Maria, Xiong, Jinhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779475/
https://www.ncbi.nlm.nih.gov/pubmed/31588901
http://dx.doi.org/10.7554/eLife.49631