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FACT mediates cohesin function on chromatin

Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here we show that the role of cohesin in chromosome organisation requires the histone chaperone FACT...

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Detalles Bibliográficos
Autores principales: Garcia-Luis, Jonay, Lazar-Stefanita, Luciana, Gutierrez-Escribano, Pilar, Thierry, Agnes, Cournac, Axel, García, Alicia, González, Sara, Sánchez, Mar, Jarmuz, Adam, Montoya, Alex, Dore, Marian, Kramer, Holger, Karimi, Mohammad Mehdi, Antequera, Francisco, Koszul, Romain, Aragon, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779571/
https://www.ncbi.nlm.nih.gov/pubmed/31582854
http://dx.doi.org/10.1038/s41594-019-0307-x