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Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry

Sphingolipids are a class of lipids that share a sphingoid base backbone. They exert various effects in eukaryotes, ranging from structural roles in plasma membranes to cellular signaling. De novo sphingolipid synthesis takes place in the endoplasmic reticulum (ER), where the condensation of the act...

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Detalles Bibliográficos
Autores principales: Wigger, Dominik, Gulbins, Erich, Kleuser, Burkhard, Schumacher, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779703/
https://www.ncbi.nlm.nih.gov/pubmed/31632963
http://dx.doi.org/10.3389/fcell.2019.00210