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Rev-erbα inhibits proliferation by reducing glycolytic flux and pentose phosphate pathway in human gastric cancer cells

Rev-erbα is a nuclear receptor, which regulates circadian rhythm, inflammatory responses and lipid metabolism. We previously showed Rev-erbα reduction in human gastric cancer, which is associated with TMN stages and poor prognosis. We hypothesized that Rev-erbα modulates proliferation via glycolytic...

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Detalles Bibliográficos
Autores principales: Tao, Linlin, Yu, Haoyuan, Liang, Rui, Jia, Ru, Wang, Jingjing, Jiang, Kai, Wang, Zhengguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779746/
https://www.ncbi.nlm.nih.gov/pubmed/31591390
http://dx.doi.org/10.1038/s41389-019-0168-5