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Deintensification of Adjuvant Treatment After Transoral Surgery in Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: The Conception of the PATHOS Study and Its Development

PATHOS is a phase II/III randomized controlled trial (RCT) of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery (TOS) for human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC). The study opened in the UK in October 2015 and, af...

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Detalles Bibliográficos
Autores principales: Hargreaves, Sarah, Beasley, Matthew, Hurt, Chris, Jones, Terry M., Evans, Mererid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779788/
https://www.ncbi.nlm.nih.gov/pubmed/31632901
http://dx.doi.org/10.3389/fonc.2019.00936