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EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca(2+) Channels
The exogenous Ca(2+) chelator EGTA (ethylene glycol tetraacetic acid) has been widely used to probe the coupling distance between Ca(2+) channels and vesicular Ca(2+) sensors for neurotransmitter release. Because of its slow forward rate for binding, EGTA is thought to not capture calcium ions in ve...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779814/ https://www.ncbi.nlm.nih.gov/pubmed/31632263 http://dx.doi.org/10.3389/fnsyn.2019.00026 |