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EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca(2+) Channels

The exogenous Ca(2+) chelator EGTA (ethylene glycol tetraacetic acid) has been widely used to probe the coupling distance between Ca(2+) channels and vesicular Ca(2+) sensors for neurotransmitter release. Because of its slow forward rate for binding, EGTA is thought to not capture calcium ions in ve...

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Detalles Bibliográficos
Autor principal:	Nakamura, Yukihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779814/ https://www.ncbi.nlm.nih.gov/pubmed/31632263 http://dx.doi.org/10.3389/fnsyn.2019.00026

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