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Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration

The aberrant expression of Wnt3 has linked to several types of human malignancies. However, it is not known for its role in tumorigenesis of colorectal cancer (CRC). Herein, we show that Wnt3 is upregulated in human CRC tissues and is essential for the CRC progression. Knockdown of Wnt3 in human CRC...

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Detalles Bibliográficos
Autores principales: Nie, Xiaobo, Xia, Fulin, Liu, Ying, Zhou, Yun, Ye, Wenling, Hean, Panha, Meng, Jiming, Liu, Huiyang, Liu, Lei, Wen, Jianxun, Ren, Xuequn, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779829/
https://www.ncbi.nlm.nih.gov/pubmed/31632267
http://dx.doi.org/10.3389/fphar.2019.01110