Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model

The deubiquitinase cylindromatosis (CYLD) is a well-known tumor suppressor, found to be down regulated in many cancer types including breast cancer, colon carcinoma and malignant melanoma. CYLD is suppressed in human melanoma cells by the transcriptional repressor SNAIL1 leading to an increase of th...

Descripción completa

Detalles Bibliográficos
Autores principales: de Jel, Miriam Martha, Schott, Mandy, Lamm, Susanne, Neuhuber, Winfried, Kuphal, Silke, Bosserhoff, Anja-Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779913/
https://www.ncbi.nlm.nih.gov/pubmed/31591386
http://dx.doi.org/10.1038/s41389-019-0169-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779913/
https://www.ncbi.nlm.nih.gov/pubmed/31591386
http://dx.doi.org/10.1038/s41389-019-0169-4

Ejemplares similares