Progranulin attenuates liver fibrosis by downregulating the inflammatory response

Progranulin (PGRN) is a cysteine-rich secreted protein expressed in endothelial cells, immune cells, neurons, and adipocytes. It was first identified for its growth factor-like properties, being implicated in tissue remodeling, development, inflammation, and protein homeostasis. However, these findi...

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Detalles Bibliográficos
Autores principales: Yoo, Wonbeak, Lee, Jaemin, Noh, Kyung Hee, Lee, Sangmin, Jung, Dana, Kabir, Mohammad Humayun, Park, Dongmin, Lee, Cheolju, Kwon, Ki-Sun, Kim, Ji-Su, Kim, Seokho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779917/
https://www.ncbi.nlm.nih.gov/pubmed/31591383
http://dx.doi.org/10.1038/s41419-019-1994-2