Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias

BACKGROUND AND PURPOSE: Early identification of drug‐induced cardiac adverse events is key in drug development. Human‐based computer models are emerging as an effective approach, complementary to in vitro and animal models. Drug‐induced shortening of the electromechanical window has been associated...

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Detalles Bibliográficos
Autores principales: Passini, Elisa, Trovato, Cristian, Morissette, Pierre, Sannajust, Frederick, Bueno‐Orovio, Alfonso, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780030/
https://www.ncbi.nlm.nih.gov/pubmed/31271649
http://dx.doi.org/10.1111/bph.14786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780030/
https://www.ncbi.nlm.nih.gov/pubmed/31271649
http://dx.doi.org/10.1111/bph.14786

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